MATERIALS SCIENCE: Feeling the Squeeze

Mechanotransduction: Feeling the Squeeze in the C. elegans Reproductive System

A new study reports that the RhoGAP SPV-1 senses membrane curvature and cell stretch in the Caenorhabditis elegans spermatheca. Without SPV-1, the cells of the spermatheca are hypercontractile, leading to deformation and rapid ejection of the fertilized eggs. The spermatheca may provide a paradigm for understanding how cells detect mechanical stimuli in vivo.

Feeling the Squeeze: Live-Cell Extrusion Limits Cell Density in Epithelia

bind both of these cellular targets to enable ferroptosis? Previous studies showed that erastin inhibits VDACmediated transport of NADH into mitochondria, thus raising the possibility that erastin’s effects on VDAC may help to elevate cytosolic levels of NADPH to support the activity of cytosolic oxidases that generate lethal levels of ROS (Yagoda et al., 2007; Yang and Stockwell, 2008). Conseq...

Linköpings universitet Materials Science Computational Materials Science from ab initio

Rajeev Ahuja use state-of-the-art theoretical methods to tackle complex material science systems at a very hight level of detail.

Journal of materials science: materials in medicine.

▶ The Journal of Materials Science: Materials in Medicine is the official journal of the European Society for Biomaterials (ESB) ▶ Covers the science and technology of biomaterials and their applications as medical or dental implants, prostheses and devices ▶ Spans a wide range of topics from basic science to clinical applications ▶ Examines the metals, ceramics, polymers and composites used in...

Materials Science Initiative Seminar: Materials for Tomorrow